Chemotherapy uses anticancer, or cytotoxic, drugs to destroy cancer cells. It is usually used to treat non-Hodgkin lymphoma NHL. Your healthcare team will consider your personal needs to plan the drugs, doses and schedules of chemotherapy. You may also receive other treatments. Chemotherapy is given for different reasons. You may have chemotherapy to: destroy cancer cells in the body destroy cancer cells in the bone marrow before a stem cell transplant relieve pain or control the symptoms of advanced NHL called palliative chemotherapy.
Cancer drugs A to Z list | | Cancer Research UK
The use of mAbs ie, rituximab or trastuzumab in the treatment of patients with B-cell lymphoma or breast cancer has improved clinical outcomes and has changed the treatment paradigm of such conditions. CD20 antigen was identified as a suitable target for mAb development in lymphoid malignancies almost 3 decades ago. While the clinical activity of rituximab is firmly established, scientific efforts had been focused on: 1 the optimization of its clinical use ie, maintenance regimens ; 2 improving its antitumor activity by combining it with novel chemotherapy agents, immunomodulatory agents, or smallmolecule inhibitors of key regulatory signaling pathways; or 3 defining the mechanisms by which rituximab kills lymphoma cells. Based on preclinical studies that characterized rituximab mechanisms of action, a new generation of humanized and more potent anti-CD20 mAbs has been generated. Obinutuzumab was re-engineered to elucidate better antibodydependent cellular cytotoxicity ADCC and a higher degree of apoptosis than rituximab, as demonstrated in laboratory models. In this article we discuss the preclinical and clinical development of this new, exciting agent. Obinutuzumab is a type 2 glyco-lengineered mAb directed against CD
Chemotherapy for non-Hodgkin lymphoma
Cancers treated with Doxorubicin include: bladder, breast, head and neck, leukemia some types , liver, lung, lymphomas, mesothelioma, multiple myeloma, neuroblastoma, ovary, pancreas, prostate, sarcomas, stomach, testis germ cell , thyroid, uterus. Cancers treated with Vincristine include: acute leukemia, Hodgkin's and non- Hodgkin's lymphoma, neuroblastoma, rhabdomyosarcoma, Ewing's sarcoma, Wilms' tumor, multiple myeloma, chronic leukemias, thyroid cancer, brain tumors. As an anti-inflammatory medication.
More information. December 21, This new product provides for a longer interval between doses compared to other available pegaspargase products. More Information. December 20,